Cardiovascular Disease Prevention Clinic at the Rasmussen Center
Cardiovascular Publications and Reference Articles
Scientific Evidence for Rasmussen Disease Score
Cohn JN, Hoke L, Whitwam W, Sommers PA, Taylor AL, Duprez D, Roessler R, Florea
N. Screening for early detection of cardiovascular disease in asymptomatic individuals.
Am Heart J 146:679-685, 2003
http://content.onlinejacc.org/cgi/content/full/52/5/327
Vascular Tests - Arterial Evaluation Tests
Large and Small Artery Elasticity Evaluation
Duprez DA, Kaiser DR, Whitwam W, Finkelstein S, Belalcazar A, Patterson R, Glasser S, Cohn JN. Arterial Stiffness, Vascular Disease, and Risk of Cardiovascular Events. Circulation. 2006;113:601-603
http://www.circ.ahajournals.org/cgi/content/full/113/5/601
Grey E, Bratteli C, Glasser SP, et al. Reduced small artery but not large artery elasticity is an independent risk marker for cardiovascular events. Am J Hypertens 2003;16:265-9
http://www.nature.com/ajh/journal/v16/n4/index.html
Cohn JN, Duprez DA, Grandits GA. Arterial elasticity as part of a comprehensive
assessment of cardiovascular risk and drug treatment. Hypertension 2005;46:217-20
http://hyper.ahajournals.org/cgi/content/abstract/01.HYP.0000165686.50890.c3v1
Resting Blood Pressure
Liszka HA, MD, Mainous III AG, King DE, Everett C, Egan BM. Prehypertension and Cardiovascular Morbidity. Annals of Family Medicine 3:294-299 (2005)
http://www.annfammed.org/cgi/content/abstract/3/4/294
Giovanni de Simone, Devereux RB, Chinali M, Roman MJ, Best LG, Welty TK, Lee ET, Howard BV. Risk Factors for Arterial Hypertension in Adults with Initial Optimal Blood Pressure The Strong Heart Study. Hypertension 2006;47:162
http://hyper.ahajournals.org/cgi/content/full/47/2/162
Blood Pressure Response During Treadmill Testing
Lim PO and MacDonald TM. Step Test in Hypertension. Q J Med 2000; 93: 703-705
http://qjmed.oxfordjournals.org/cgi/content/full/93/11/703
Singh JP, Larson MG, ScD, Manolio TA, O'Donnell CJ, Lauer M, Evans JC, Levy D. Blood Pressure Response During Treadmill Testing as a Risk Factor for New-Onset Hypertension. The Framingham Heart Study. Circulation. 1999;99:1831-1836
http://www.ncbi.nlm.nih.gov/pubmed/10199879
Retinal Vessels Evaluation
Harry A.J. Struijker-Boudier. Retinal Microcirculation and Early Mechanisms of Hypertension. Hypertension. 2008;51:821
http://hyper.ahajournals.org/cgi/content/full/hypertensionaha;51/4/821
Jie Jin Wang; Tien Yin Wong. Genetic Determinants of Retinal Vascular Caliber Additional Insights Into Hypertension Pathogenesis. Hypertension. 2006;47:644
http://hyper.ahajournals.org/cgi/content/full/hypertensionaha;47/4/644
Carotid Artery Intima-Media Thickness (IMT) Ultrasound
Nambi V, Chambless L, Folsom AR, He M, Hu Y, Mosley T, Volcik K, Boerwinkle E, Ballantyne CM. Carotid Intima-Media Thickness and presence or Absence of Plaque Improves Prediction of Coronary Heart Disease Risk. J Am Coll Cardiol. 2010 Apr 13;55(15):1600-7
http://content.onlinejacc.org/cgi/content/short/55/15/1600
Urinary albumintest for Micro-albuminuria excretion
Borch-Johnsen K, Feldt-Rasmussen B, Strandgaard S, et al. Urinary albumin excretion:
an independent predictor of ischemic heart disease. Arterioscler Thromb Vasc Biol
1999;19:1992-7
http://atvb.ahajournals.org/cgi/content/full/19/8/1992
Hillege HL, Fidler V, Diercks GF, et al. Prevention of Renal and Vascular End Stage
Disease (PREVEND) Study Group. Urinary Albumin Excretion Predicts Cardiovascular
and Noncardiovascular Mortality in General Population. Circulation 2002;106: 1777-82
http://circ.ahajournals.org/cgi/content/abstract/106/14/1777
Cardiac Tests - Heart Evaluation Tests
ECG
Kannel WB, Abbott RD. A Prognostic Comparison of Asymptomatic Left Ventricular
Hypertrophy and Unrecognized Myocardial Infarction: The Framingham Study.
Am Heart J 1986;111:391-7
http://www.ncbi.nlm.nih.gov/pubmed/2936230
Plasma Natriuretic Peptide (BNP)
Wang TJ, Larson MG, Keyes MJ, Levy D, Benjamin EJ et al. Plasma Natriuretic Peptide Levels and the Risk of Cardiovascular Events and Death. N Engl J Med 2004;350:655-63
http://content.nejm.org/cgi/reprint/350/7/655.pdf
Wang TJ, Larson MG, Keyes MJ, Levy D, Benjamin EJ, Vasan RS. Association of Plasma Natriuretic Peptide Levels With Metabolic Risk Factors in Ambulatory Individuals. Circulation. 2007;115:1345-1353
http://circ.ahajournals.org/cgi/content/full/115/11/1345
Cardiac Ultrasound
Wang TJ, Levy D, Benjamin EJ, Vasan RS. The Epidemiology of "Asymptomatic" Left
Ventricular Systolic Dysfunction: Implications for Screening.
Ann Intern Med 2003;138: 907-16
http://www.annals.org/content/138/11/907.full.pdf+html
Abdominal Aortic Aneurism
Johnsen SH, Forsdahl SH, Singh K, Jacobsen BK. Atherosclerosis in Abdominal Aortic Aneurysms: A Causal Event or a Process Running in Parallel? The Tromso Study. JAHA Arterioscler Thromb Vasc Biol. 2010:30:00-0
http://atvb.ahajournals.org/cgi/content/short/ATVBAHA.110.203588
Other Manuscripts and Abstracts from Rasmussen Center
Duprez DA, Somasundaram PE, Sigurdsson G, Hoke L, Florea N, Cohn JN. Relationship between C-reactive protein and arterial stiffness in an asymptomatic population. J Hum Hypertens 19(7):515-9, 2005.
Duprez D, De Buyzere M, Van Den Noortgate N, Simoens J, Achten E, Afschrift M, Cohn JN . Relation between periventricular or deep white matter lesions and arterial elasticity indices in very old people. Age and Aging 30:325-330, 2001.
Duprez D, De Buyzere ML, De Bruyne L, Clement DL, Cohn JN. Small and large artery elasticity indices in peripheral arterial occlusive disease (PAOD). Vascular Medicine 6:211-214, 2001.
Siggurdsson G, Withwam W, Hoke L, Duprez D, Cohn JN. Noninvasive pulse contour analysis associated with microalbuminuria. JACC, 41, 6, Suppl A, 263A, 2003.
holakanahalli VN, Duprez D, Hoke L, Cohn J. Elevated brain natriuretic peptide levels are related to impaired small artery elasticity. JACC, 41, 6, Suppl A, 286A, 2003.
Somasundaram PE, Duprez DA, Sigurdsson G, McKnite SH, Hoke L, Florea N, Cohn JN. CRP Is associated with increased large artery stiffness in a primary prevention population. Am J Hypertension 16, 5 Pt2, 5A, 2003.
Sigurdsson G, Duprez DA, Hirsch AT, Florea N, Hoke L, Cohn JN. Supranormal ankle brachial index is associated with a favorable exercise blood pressure response. Am J Hypertension 16, 5 Pt 2, 161 A, 2003.
Duprez DA, Sigurdsson G, P Dasari, Florea N, Hoke L, Cohn JN. Differences in brain- natriuretic peptide and left ventricular dimensions and mass in normotension, prehypertension and hypertension. JACC 43, suppl A, 512A, 2004.
Duprez DA, W Witwam, DR Kaiser, SM Finkelstein, SP Glasser, A Belalcazar, R Patterson, Cohn JN. Systolic reflective index: a new parameter to study arterial elasticity. JACC 43, suppl A, 528A, 2004.
Duprez DA, PE Somusandaram, Florea N, Hoke L, Cohn JN. Are arterial stiffness and micro-albuminuria in pre-hypertensives different from normotensives and hypertensives? Am J Hypertension 17, 5Pt2, 130A, 2004.
Duprez DA, K Straith, Florea N, Cohn JN. C-reactive protein is related to an increased blood pressure response during exercise in a primary prevention population. Am J Hypertension 17, 5Pt2, 149A, 2004.
Florea N, Hoke L, Sommers PA, Taylor AL, Cohn JN, Duprez D. Gender differences in new markers for early detection of cardiovascular disease in asymptomatic individuals. Circulation, 111, E-50-51, 2005.
Bransford TL, Duprez D, W Whitwam, Florea N, Hoke L, Cohn J. Peri-menopausal differences in QT-corrected interval. Circulation, 111, E-84, 2005.
Duprez DA, Florea N, Hoke L, Killpatrick B, Cohn JN. Exercise blood pressure response is inversely related to large artery, but not to small artery elasticity. Am J Hypertension 18, 5Pt2: 12 A-13A, 2005.
Duprez DA, Kaiser DR, Florea N, Hoke L, Killpatrick B, Cohn J. Role of gender on the relationship between brain-natriuretic peptide (BNP) and left ventricular dimensions. Am J Hypertension 18, 5Pt2: 187 A, 2005.
Duprez DA, Florea N, Kilpatrick B, Hoke L, Cohn JN. Valsartan increases small arterial elasticity in asymptomatic individuals. Am J Hypertension 18, 5Pt2: 224 A, 2005.
Wu FM, Duprez DA, Florea N, Jones K, Hoke L, Cohn JN. Progressive decrease in large and small artery elasticity with the presence of multiple components of the metabolic syndrome. JACC 47;suppl A: 312A, 2006.
Murray S, Nguyen J, Duprez D, Florea N, Hoke L, Cohn JN. The heterogenous influence of metabolic risk factors on arterial elasticity. JACC 47; suppl A: 346A, 2006.
Jordan CO, Duprez D, Florea N, Hoke L, Cohn JN. Gender difference of small and large artery elasticity in relation to pulse pressure. JACC 47; suppl A: 347A, 2006.
Duprez DA, Florea N, Jones K, Hoke L, Cohn JN. Beneficial effects of valsartan on the Rasmussen risk score in asymptomatic individuals at high risk. J Clin Hypertension 2006;8:Suppl A:A44-P88.
Duprez D, Florea N, Grandits G, Neaton J, Jones LK, Hoke L, Cohn JN. Gender-Difference in Brain-Natriuretic Peptide (BNP) Reflects Different Cardiac Remodeling. Circulation 2006;114.